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Effect on cardiac markers One animal study demonstrated that administration of LC mitigated the cardiotoxic effects of trazodone (TRZ)-induced cardiotoxicity by normalizing levels of creatine kinase-MB (CK-MB), aspartate transaminase (AST), and cardiac troponin I (cTnI) compared to TRZ only group

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That is why side effects often peak during titration and settle down later

found that mild electrical stimulation (MES) combined with heat shock (HS) attenuated inflammatory symptoms in a mouse model of imiquimod-induced psoriasis [130]